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secobarbital will lower the extent or effect of etoposide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.secobarbital will lessen the extent or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Recommended atogepant dosage with concomitant utilization of pote